20 May 2010

Fahr Disease

Unenhanced CT shows symmetric bilateral calcifications in the basal ganglia: nucleus caudatus, globus pallidus, pulvinar in a 30 years old man. Most likely it is the case of Fahr disease however basal ganglia calcifications have a long list of differential diagnosis including metabolic diseases and hypoparathyroidism. Further workup (clinical and with MRI) is of value.

See also: Fahr disease from Neuroradiology On the Net

Differential diagnosis may also include a rare type of mitochondrial disease.
Yutaka Nishigaki - A novel mitochondrial tRNALeu(UUR) mutation in a patient with features of MERRF and Kearns–Sayre syndrome