Brain Degenerative Diseases and Gut Flora

Coronal CT of 86 years old showing moderate atrophy i hippocampi - MTA 2. Interesting articles indicate complex relation between our gut flora and neurodegenerative diseases. Especially in Alzheimer Dementia (AD). Gut Microbiota Regulation and Their Implication in the Development of Neurodegenerative Disease - Peilin Sun, Et al. Downregulation of Neurofilament Light Chain Expression in Human Neuronal-Glial Cell Co-Cultures by a Microbiome-Derived Lipopolysaccharide-Induced miRNA-30b-5p - Aileen I. Pogue, Et al. *(citations from above articles in cursive font) Studies indicate that anaerobic bacteria producing toxins cause brain inflammation that disrupts fragile neural connections in the elderly. My private theory is that hygiene of the mouth plays important role. Environmental factors of the modern civilisation, food preservatives and destruction of natural gut flora plays important role. Also fact that people live longer allows more time for neurodegenerative diseases to develop. O