Gobbi CEC Syndrome (Celiac Disease, Epilepsy, and Cerebral Calcifications)
What do you do when a routine brain CT for non-specific headaches reveals striking, dense, bilateral calcifications, but the clinical exam is completely unremarkable? In our latest teaching case on RP Radiology - Radiant Pixels , we break down a fascinating case of a 40-year-old patient whose neuroimaging keys open a door to a completely unexpected systemic diagnosis. The Imaging Dilemma: Symmetrical but Atypical When encountering prominent, symmetrical intracranial mineralization on a non-contrast CT, the classic reflex is to think of Fahr’s disease (primary familial brain calcification). However, this case reminds us why location is everything in neuroradiology. While Fahr's characteristically targets the deep gray matter, this patient's basal ganglia, thalami, and dentate nuclei were completely pristine. The dense calcifications were strictly restricted to the cortical and subcortical regions of the bilateral occipital lobes. To investigate further, we performed an MRI, w...