15 August 2011

Gadolinium Guidelines


T1 with iv Gadolinium and T2 showing non-enhancing, pathology verified Astrocytoma grade 2 in the medial parts of the left temporal lobe. Note distortion of the brain architecture.

However subject of this post concerns Gadolinium Guidelines in attention to Nephrogenic Systemic Fibrosis. Here is the summary:


Gadolinium Guidelines

- eGFR 60 or greater - OK
- eGFR 30-59 - weight-based dose of GBCA (0.2 mL/kg) can be administered with maximal dose of 20 mL allowed within 24 hours
- eGFR less than 30 - GBCA cannot be administered except in cases of medical necessity; informed consent required; nephrology consultation required; hemodialysis should be considered


According to:
Yingbing Wang - Incidence of Nephrogenic Systemic Fibrosis after Adoption of Restrictive Gadolinium-based Contrast Agent Guidelines