04 January 2010

Wallerian Degeneration

CT without contrast shows status after old MCA infarct on the right. Note hypodense degeneration in the corticospinal pyramidal tracts on the corresponding side. Wallerian Degeneration (WaD) is a secondary anterograde degeneration of axons and their myelin sheaths caused by proximal axonal or neuronal cell body lesions. MR would show those changes even better.