First Frost in December

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December brought some frost and leaves are down.

But first was fog.

That's Alf in the web. ;-)

Then came frost.

Most of the photos are by my talented wife Anna @Myszuwa

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Patient presented with expressive dysphasia . MRI shows acute infarct in Broca's Area in the left inferior frontal gyrus that is responsible for speech production. Note high signal on DWI, low on corresponding ADC as well as signal changes on T2 and coronal FLAIR.
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10 years old boy from parents being cousins to each other presents with progressive rigidity and dystonia. Initial MR showing significant bilateral atrophy in caudate nuclei and putamina with high signal on FLAIR and T2 consistent with gliosis. Note striking symmetric atrophy of the putamina and caudate nuclei on T2 and IR. Huntington disease (HD) is also known as Huntington chorea. HD is an autosomal dominant chronic hereditary neurodegenerative disorder with complete penetrance [Osborn].  Aggregates of huntingtin protein accumulate in axonal terminals, which eventually leads to the death of medium spiny neurons. Autopsy shows generalized cerebral atrophy with an average of 30% reduction in brain weight. Both the cortex and hemispheric WM are affected. The most characteristic gross abnormality is volume loss with rarefaction of the caudate nucleus, putamen, and globus pallidus [Osborn].  Microscopically, HD features neuronal loss with huntingtin nuclear inclusi...
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